Link Prediction via Community Detection in Bipartite Multi-Layer Graphs

International audienceThe growing number of multi-relational networks pose new challenges concerning the development of methods for solving classical graph problems in a multi-layer framework, such as link prediction. In this work, we combine an existing bipartite local models method with approaches for link prediction from communities to address the link prediction problem in multi-layer graphs. To this end, we extend existing community detection-based link prediction measures to the bipartite multi-layer network setting. We obtain a new generic framework for link prediction in bipartite multi-layer graphs, which can integrate any community detection approach, is capable of handling an arbitrary number of networks, rather inexpensive (depending on the community detection technique), and able to automatically tune its parameters. We test our framework using two of the most common community detection methods, the Louvain algorithm and spectral partitioning, which can be easily applied to bipartite multi-layer graphs. We evaluate our approach on benchmark data sets for solving a common drug-target interaction prediction task in computational drug design and demonstrate experimentally that our approach is competitive with the state-of-the-art

Yearb Med Inform

OBJECTIVES: To introduce the 2022 International Medical Informatics Association (IMIA) Yearbook by the editors. METHODS: The editorial provides an introduction and overview to the 2022 IMIA Yearbook whose special topic is "Inclusive Digital Health: Addressing Equity, Literacy, and Bias for Resilient Health Systems". The special topic, survey papers, section editor synopses and some best papers are discussed. The sections' changes in the Yearbook Editorial Committee are also described. RESULTS: As shown in the previous edition, health informatics in the context of a global pandemic has led to the development of ways to collect, standardize, disseminate and reuse data worldwide. The Corona Virus Disease 2019 (COVID-19) pandemic has demonstrated the need for timely, reliable, open, and globally available information to support decision making. It has also highlighted the need to address social inequities and disparities in access to care across communities. This edition of the Yearbook acknowledges the fact that much work has been done to study health equity in recent years in the various fields of health informatics research. CONCLUSION: There is a strong desire to better consider disparities between populations to avoid biases being induced in Artificial Intelligence algorithms in particular. Telemedicine and m-health must be more inclusive for people with disabilities or living in isolated geographical areas

Improving semantic information retrieval by combining possibilistic networks, vector space model and pseudo-relevance feedback

International audienceTo improve the performance of information retrieval systems (IRSs), we propose in this article a novel approach that enriches the user’s queries with new concepts. Indeed, query expansion is one of the best methods that plays an important role in improving searches for a better semantic information retrieval. The proposed approach in this study combines possibilistic networks (PNs), the vector space model (VSM) and pseudo-relevance feedback (PRF) to evaluate and add relevant concepts to the initial index of the user’s query. First, query expansion is performed using PN, VSM and domain knowledge. PRF is then exploited to enrich, in a second round, the user’s query by applying the same approach used in the first expansion step. To evaluate the performance of the developed system, denoted conceptual information retrieval model (CIRM), several experiments of query expansion are performed. The experiments carried out on the OHSUMED and Clinical Trials corpora showed that using the two measures of possibility and necessity combined the cosinus similarity and PRF improves the query expansion process. Indeed, the improvement rate of our approach compared with the baseline is +28, 49% in terms of P@5

Managing large-scale genomic datasets and translation into clinical practice.

International audienceTo summarize excellent current research in the field of Bioinformatics and Translational Informatics with application in the health domain

Efficient Results in Semantic Interoperability for Health Care

International audienceTo summarize excellent current research in the field of Knowledge Representation and Management (KRM) within the health and medical care domain

Bioinformatics Methods and Tools to Advance Clinical Care

International audienceTo summarize excellent current research in the field of Bioinformatics and Translational Informatics with application in the health domain and clinical care

From genome sequencing to bedside. Findings from the section on bioinformatics and translational informatics.

International audienceTo summarize excellent current research in the field of Bioinformatics and Translational Informatics with application in the health domain and evidence-based medicine